DESIRIAL® is the world’s first treatment based on cross-linked hyaluronic acid for women suffering from vaginal dryness and other symptoms related to vulvo-vaginal atrophy. DESIRIAL® is available in two gel formulations carefully developed to treat distinct pathologies according to the intended treatment indications:
|Desirial® is dedicated to trophic conditions restoration (hydration, elasticity, tone, sensitivity) in the vulvo-vaginal area.
It helps to reduce mucosal dryness and strengthen delicate vaginal tissues, making them more supple.
|DESIRIAL® PLUS is a more cohesive gel. It can correct morphological vulvar imperfections. In addition to aesthetic corrections, it also fights against functional disorders, such as severe to moderate vaginal atrophy of the labia majora.|
DESIRIAL® and DESIRIAL® PLUS are the only injectable hyaluronic acid based medical devices on the market that are CE registred for gynaecological indications, e.g., rejuvenation of the vaginal mucosa, or reconstruction of the labia majora.
It means that DESIRIAL® complies with all relevant legal requirements and safety standards such as biocompatibility and tolerance. These gels have unique rheological properties in order to ensure that the product is well adapted for safe use in the delicate genital area taking into consideration the anatomical features of the vulvo-vaginal region.
In 2007, Laboratoires VIVACY® patented the IPN-Like Technology, a unique, advanced HA cross-linking process that makes it possible to design high performance products with special properties for medical and aesthetic applications.
Mannitol is a natural antioxidant, found in a large variety of natural products, including plants. It is widely used in the pharmaceutical industry and has been incorporated into DESIRIAL® products to preserve the physico-chemical functions of hyaluronic acid:
When a needle is inserted in the skin, it triggers free-radicals generation. Those molecules are very reactive and can be deleterious for the gel. Hence, mannitol, a free-radical scavenger, has been added to the product formulation. It contributes significantly to the DESIRIAL® protection from free radicals actions. The result is an optimization of the product duration in the tissues.
Mannitol is also hygroscopic, which means that it attracts water. Hence, it contributes also to the hydration capabilities of DESIRIAL®. Given that water retention capabilities are very important to improve the mucosal trophism, mannitol is important for DESIRIAL® efficacy.